His early work was concerned with the cell cycle and under the supervision of Sir Tim Hunt, Jon was the first to clone cyclin B – the critical protein for regulating mitosis in animal cells. Later, with Tony Hunter, Jon began to focus on the spatial organisation of mitotic regulators and in his own lab pioneered the use of fluorescent protein tags to analyse the dynamic behaviour and stability of these regulators in living cells.
Jon has made key discoveries in the cell cycle field, many of which have opened up new avenues of research. His discoveries revealed that mitotic regulators are targeted to specific substructures at specific times, and that mitosis is exquisitely coordinated by the destruction of key regulators at different times in cell division; insights which have wider implications for how cancers develop.
Jon had this to say regarding his new position and the future of the Journal:
“As the new Editor-in-Chief I first wish to thank David Glover, the founding Chief Editor, who managed in a remarkably short period of time to establish Open Biology as a respected and widely recognised international journal for Cell and Molecular Biology. I hope to build on these firm foundations while taking advantage of the rapid developments in preprints, open access and transparent peer-review. Open Biology will continue to be a supportive home to publish important research advances, but – as its name indicates – Open Biology will also be open to new ideas and new concepts in Science: we will be introducing forums to stimulate discussion (Open Questions) and to challenge dogma (Open Up). We will also be open to new ways of publishing and reviewing. In these endeavours, I am delighted that we have such an enthusiastic and innovative Editorial Board supported by such dedicated editorial staff at the Royal Society.”
Jon has been a member of the Open Biology editorial board since its inception in 2011. In a recent blog post, we asked him his thoughts on what makes a great paper.
Open Biology is looking to publish more high quality research articles in cellular and molecular biology. Find out more about our author benefits and submission process.
Image credit: Professor Jonathon Pines FRS, Institute of Cancer Research, UK © The Royal Society